发明名称 NITROGEN-CONTAINING SIX-MEMBERED AROMATIC RING DERIVATIVES AND PHARMACEUTICAL PRODUCTS CONTAINING THE SAME
摘要 Compounds of Formula (I) promote axonal outgrowth angiogenesis and can therefore be used to reduce central nerve injuries such as head injury and spinal cord injury, cerebral infarction, ischemic heart diseases, peripheral arterial occlusive diseases, or after-effects of these diseases. in which Nx group is preferably a 6-membered aromatic ring containing two nitrogen atoms; R0, R1 and R2 are each independently a hydrogen atom, an alkyl group, or an amino group; E is an oxygen atom or an —NR8 group (wherein R8 is an alkyl group or the like); n is an integer of 0 to 5; X and Y are each a connecting bond, a cycloalkyl group, or —CO—; and Q is a hydrogen atom or a phenyl group.
申请公布号 US2012258978(A1) 申请公布日期 2012.10.11
申请号 US201213482375 申请日期 2012.05.29
申请人 TAKEMOTO NAOHIRO;MURATA KENJI;MURAYAMA NORIHITO;YAMADA CHIKAOMI;DAIICHI SANKYO COMPANY, LIMITED 发明人 TAKEMOTO NAOHIRO;MURATA KENJI;MURAYAMA NORIHITO;YAMADA CHIKAOMI
分类号 A61K31/506;A61P9/00;A61P9/10;A61P25/00;A61P25/14;A61P25/16;A61P25/28;C07D401/12;C07D401/14 主分类号 A61K31/506
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