发明名称 PROCESS FOR PREPARING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR
摘要 The present invention relates to processes for preparing solid state forms of N-(4-(7-azabicyclo[2.2.1]heptan-7-yl)-2-(trifluoromethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxamide, including Compound 1 Form A, Compound 1 Form A-HCl, Compound 1 Form B, and Compound 1 Form B-HCl, any combination of these forms, pharmaceutical compositions thereof, and methods of treatment therewith.
申请公布号 KR20120104554(A) 申请公布日期 2012.09.21
申请号 KR20127013136 申请日期 2010.10.21
申请人 VERTEX PHARMACEUTICALS INCORPORATED 发明人 AMBHAIKAR NARENDRA BHALCHANDRA;HUGHES ROBERT;HURLEY DENNIS JAMES;LEE ELAINE CHUNGMIN;LITTLER BENJAMIN;NUMA MEHDI;ROEPER STEFANIE;SHETH URVI
分类号 C07D487/08;A61K31/407;A61P1/00;C07D401/12 主分类号 C07D487/08
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