MITOCHONDRIAL MUTATION AND REARRANGEMENT AS DIAGNOSTIC TOOL FOR DETECTION OF SUN EXPOSURE, PROSTATE CANCER AND OTHER CANCERS

摘要

PROBLEM TO BE SOLVED: To provide methods and kits for detecting mitochondrial DNA deletions for the early detection, diagnosis and progression of prostate cancer, sun exposure and non-melonoma skin cancer.

SOLUTION: The method for detecting a predisposition to cancer, early detection of cancer, genesis of cancer, presence of cancer, progression of cancer, absence of cancer, or sun exposure in a biological sample having mitochondrial DNA (mtDNA) includes (a) providing a biological sample comprising mtDNA and (b) detecting a deletion in the mtDNA.

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