发明名称 |
Enhanced FC receptor-mediated tumor necrosis factor superfamily MRNA expression in peripheral blood leukocytes in patients with rheumatoid arthritis |
摘要 |
A method for predicting patient responsiveness to rheumatoid arthritis treatments involving altering expression of tumor necrosis factor superfamily (“TNFSF”)-2, TNFSF-8, or TNFSF-15 is disclosed. A method for monitoring the effectiveness of such therapy is also disclosed. Furthermore, a method of screening compounds for use in the treatment of rheumatoid arthritis is disclosed. A method of monitoring the disease state over time in rheumatoid arthritis patients is also disclosed.
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申请公布号 |
US8268566(B2) |
申请公布日期 |
2012.09.18 |
申请号 |
US20080743220 |
申请日期 |
2008.11.11 |
申请人 |
MITSUHASHI MASATO;ENDO KATSUYA;OBARA KAZUHIKO;IZUTSU HIROSHI;OHTA SHUJI;HITACHI CHEMICAL RESEARCH CENTER, INC.;HITACHI CHEMICAL CO., LTD. |
发明人 |
MITSUHASHI MASATO;ENDO KATSUYA;OBARA KAZUHIKO;IZUTSU HIROSHI;OHTA SHUJI |
分类号 |
C12Q1/68;A61K38/17;A61K39/395;A61P19/02;C07K14/425;C12N5/078 |
主分类号 |
C12Q1/68 |
代理机构 |
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地址 |
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