发明名称 |
Method for enantioselective hydrogenation of chromenes |
摘要 |
A method for preparing an enantiomeric chromane, by asymmetrically hydrogenating a chromene compound in the presence of an Ir catalyst having a chiral ligand. The method includes the enantioselective preparation of enantiomeric equol. A preferred Ir catalyst has a chiral phosphineoxazoline ligand. Enantiomeric chromanes of high stereoselective purity can be obtained.
|
申请公布号 |
US8263790(B2) |
申请公布日期 |
2012.09.11 |
申请号 |
US201113150414 |
申请日期 |
2011.06.01 |
申请人 |
SETCHELL KENNETH DAVID REGINALD;SOROKIN VICTOR DMITRIEVICH;CHILDREN'S HOSPITAL MEDICAL CENTER;GIRINDUS AMERICA, INC. |
发明人 |
SETCHELL KENNETH DAVID REGINALD;SOROKIN VICTOR DMITRIEVICH |
分类号 |
C07D311/00 |
主分类号 |
C07D311/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|