| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide an adhesive preparation which has a low irritation to the skin surface, is superior in stability of bisoprolol in the preparation and further is capable of continuously administrating an effective amount of bisoprolol for treatment or prevention to the living body. <P>SOLUTION: The adhesive preparation 10 has a support 1 and an adhesive layer 2 which is layered on one surface of the support 1. The adhesive layer 2 is characterized by containing bisoprolol, polyisobutylene, a tackifier and an organic liquid component which is compatible with polyisobutylene and tackifiers. Thus, the adhesive preparation having good skin adhesiveness, low skin irritation and reduced pain or adhesive residue at the time of removal from the skin surface can be provided. Further, the adhesive preparation in which the stability of bisoprolol in the adhesive preparation is excellent and an effective amount of bisoprolol for treatment and prevention can be continuously administrated to the living body through the skin surface is provided. <P>COPYRIGHT: (C)2012,JPO&INPIT |
