发明名称 |
Treatment of ocular neovascular disorders such as macular degeneration, angiod streaks, uveitis and macular edema |
摘要 |
<p>The present invention is directed to methods of treating an ocular neovascular disorder in a mammal by administration of pyrimidine derivatives, benzodiazepinyl derivatives and pharmaceutical compositions containing the same. The invention encompasses methods of treating an ocular neovascular disorder by administration of 5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide, (S)-3-oxo-8-[3-(pyridin-2-ylamino)-1-propyloxy]-2-(2,2,2-trifluoroethyl)-2,3,4,5-tetrahydro-1H-2-benzazepine-4-acetic acid or salts or solvates thereof. Combination therapies for the treatment of ocular neovascular disorders are also encompassed.</p> |
申请公布号 |
EP2329821(B1) |
申请公布日期 |
2012.08.22 |
申请号 |
EP20100170798 |
申请日期 |
2006.11.29 |
申请人 |
GLAXOSMITHKLINE LLC |
发明人 |
BRIGANDI, RICHARD ANTHONY;LEVICK, MARK;MILLER, WILLIAM HENRY |
分类号 |
A61K31/506;A61K31/55;A61K31/7052;A61K39/395;A61P27/02 |
主分类号 |
A61K31/506 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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