发明名称 |
DIAGNOSTIC AND TREATMENT FOR CHRONIC AND ACUTE PHASE MYELOID LEUKEMIA |
摘要 |
Disclosed are methods of predicting responsiveness of a cancer cell to a tyrosine kinase inhibitor, and methods of predicting the risk of progression of a cancer cell to a more aggressive form. Also provided are methods of reducing proliferation or promoting differentiation of a cancer cell having reduced level of Numb or increased level of Msi. Further disclosed are methods of treating a mammalian subject having cancer and methods of assessing an agent for chemotherapeutic potential.
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申请公布号 |
US2012208188(A1) |
申请公布日期 |
2012.08.16 |
申请号 |
US201013320324 |
申请日期 |
2010.05.14 |
申请人 |
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发明人 |
REYA TANNISHTHA;KWON HYOG Y.;ITO TAKAHIRO;KIM DONG-WOOK;OEHLER VIVIAN;RADICH JERALD |
分类号 |
C12Q1/68;C12N5/09;C12N15/85;C12Q1/06;G01N21/64;G01N33/53 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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