发明名称 |
Kinase substrates |
摘要 |
Tyrosine kinase substrates are described herein that are phosphorylated by many and diverse tyrosine kinases, and are chemically stable relative to co-polymers of poly-EY or poly-EAY having random molecular weights in the range of 20-50 kDa. Tyrosine kinase substrate peptides are provided according to embodiments described herein which include an isolated tyrosine kinase substrate peptide having molecular weight in the range of about 0.5 kD-10 kD. Tyrosine kinase substrate peptides are provided according to embodiments described herein having no more than 50 amino acids. The peptides include 2-25 phosphorylation modules and each phosphorylation module has 2-3 amino acid residues. |
申请公布号 |
US8242083(B2) |
申请公布日期 |
2012.08.14 |
申请号 |
US20090490031 |
申请日期 |
2009.06.23 |
申请人 |
BEAUDET LUCILLE;ROBY PHILIPPE;BLOUIN JULIE;PERKINELMER HEALTH SCIENCES, INC. |
发明人 |
BEAUDET LUCILLE;ROBY PHILIPPE;BLOUIN JULIE |
分类号 |
A61K38/10;A61K38/16;G01N33/533 |
主分类号 |
A61K38/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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