| 摘要 |
The present invention relates to a method of treating a disease or disorder characterised by increased stress hormone levels and/or decreased androgen hormone levels in a subject, comprising administering to the subject a therapeutically effective amount of a compound represented by formula (I): wherein n is 1 or 3; R is hydrogen or --C(O)N(R<sub>a</sub>)(R<sub>b</sub>) wherein R<sub>a</sub> and R<sub>b</sub> are independently --(C<sub>1</sub>-C<sub>4</sub>) alkyl, or --(C<sub>1</sub>-C<sub>4</sub>) alkyl-(C<sub>5</sub>-C<sub>7</sub>) aryl, wherein each of R<sub>a</sub> and R<sub>b</sub> is optionally substituted by --(C<sub>1</sub>-C<sub>4</sub>) alkoxy; R<sub>1</sub>, R<sub>2</sub>, and R<sub>3</sub>, are independently hydrogen, halogen, cyano or --(C<sub>6</sub>-C<sub>10</sub>) aryl, wherein said --(C<sub>6</sub>-C<sub>10</sub>) aryl is optionally substituted by halogen, with the proviso that no more than one of R<sub>1</sub>, R<sub>2</sub>, and R<sub>3</sub> is hydrogen; and R<sub>4</sub> and R<sub>5</sub> are hydrogen; or a pharmaceutically acceptable salt thereof. |
