NEW COMPOUND, PHARMACEUTICAL COMPOSITION AND USE OF THE SAME

摘要

PROBLEM TO BE SOLVED: To solve the problem in which conventional compounds cannot sufficiently exert an inhibitory effect on DHODH (dihydroorotate dehydrogenase).

SOLUTION: There are provided a compound such as 2-(cyclopropanecarbonyl-amino)-5-(2-phenylacetylamino-phenoxy)-benzoic acid, and a compound selected from salts thereof coupled with pharmaceutically allowable inorganic cations, which are used to provide the compound and pharmaceutical composition effective for clinical treatment of autoimmune disease, inflammatory disease, rejection to organ transplant and malignant neoplasm.

COPYRIGHT: (C)2012,JPO&INPIT