发明名称 |
ASSESSMENT OF IGF-1 LEVELS IN HIV-INFECTED SUBJECTS AND USES THEREOF |
摘要 |
Improved methods for determining normal IGF-1 levels in HIV infected subjects, based on a determination of the log of IGF-1 values obtained in blood-derived samples from a population of HIV-infected subjects, are disclosed. Also disclosed are methods of determining whether a given HIV-infected subject exhibits a normal IGF-1 level, based on a comparison of either the IGF-1 value or the log of the IGF-1 value obtained from a blood-derived sample of the subject with a normative IGF-1 range determined using the exponentiation of the log of IGF-1 values or the log of IGF- values obtained in blood-derived samples from a population of age- and gender-matched HIV- infected subjects. Such methods are useful for example to monitor GH stimulation therapy in HIV- infected subjects. |
申请公布号 |
WO2012094755(A1) |
申请公布日期 |
2012.07.19 |
申请号 |
WO2012CA50012 |
申请日期 |
2012.01.11 |
申请人 |
THERATECHNOLOGIES INC.;POTVIN, DIANE |
发明人 |
POTVIN, DIANE |
分类号 |
G01N33/68;A61K38/27;G01N33/53;G06F19/00 |
主分类号 |
G01N33/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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