METHODS FOR REMOVAL OF VECTOR FRAGMENTS IN SEQUENCING LIBRARY AND USES THEREOF

摘要

Methods for removal of vector fragments in sequencing library, methods for sequencing clone library of genomes and kits for sequencing genomes are provided. Wherein methods for removal of vector fragments in sequencing library include: providing labeled probes which are able to hybridize with vector fragments; hybridizing the probes with the sequencing library, so that the probes and the vector fragments form labeled double-stranded nucleic acid; and utilizing labeled molecular entity on specific binding probes to remove labeled double-stranded nucleic acid, accordingly remove vector fragments in sequencing library.