| 发明名称 |
MATRICES FOR DRUG DELIVERY AND METHODS FOR MAKING AND USING THE SAME |
| 摘要 |
In one aspect, biocompatible matrices such as sol-gels encapsulating a reaction center may be administered to a subject for conversion of prodrugs into biologically active agents. In certain embodiments, the biocompatible matrices of the present invention are sol-gels. In one embodiment, the enzyme L-amino acid decarboxylase is encapsulated and implanted in the brain to convert L-dopa to dopamine for treatment of Parkinson's disease.
|
| 申请公布号 |
CA2328614(C) |
申请公布日期 |
2012.06.26 |
| 申请号 |
CA20002328614 |
申请日期 |
2000.02.14 |
| 申请人 |
BIOSTREAM, INC. |
发明人 |
BABICH, JOHN W.;BONAVIA, GRANT;ZUBIETA, JON |
| 分类号 |
A61K38/44;A61K47/04;A61K9/10;A61K31/198;A61K35/407;A61K38/43;A61K45/08;A61K47/48;A61L31/16;A61P25/16;C12N11/14;C12Q1/00;C12Q1/25;G01N33/53;G01N33/543;G01N33/552;G01N33/68 |
主分类号 |
A61K38/44 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
