摘要 |
<P>PROBLEM TO BE SOLVED: To provide a high safety antagonist agent for an oxidized LDL receptor LOX-1 which is expressed by a vascular endothelial cell, macrophage or the like, and to provide a food composition, and a prophylactic agent and a therapeutic agent of a cardiovascular disease or cancer containing the same. <P>SOLUTION: The antagonist agent comprises flavonoid gallate shown by the following formula (1) as an active ingredient. In the formula, R1-R4 are H or -CH3, R5-R8 are H, -OH or -OCH3, R1-R4 each may be the same group or the different group, and R5-R8 each may be the same group or different group. <P>COPYRIGHT: (C)2012,JPO&INPIT |