发明名称 |
CARDIAC MUSCLE REPAIR OR REGENERATION USING BONE MARROW-DERIVED STEM CELLS |
摘要 |
Disclosed are compositions and methods for repairing and/or regenerating cardiac tissue by administering adult bone marrow-derived stem cells to an individual. These cells can be administered as a liquid injectible or as a preparation of cells in a matrix which is or becomes solid or semi-solid. The cells can be genetically modified to enhance myocardial differentiation and integration. Also disclosed is a method for replacing cells ex vivo in a heart valve for implantation.
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申请公布号 |
US2012141438(A1) |
申请公布日期 |
2012.06.07 |
申请号 |
US201213370009 |
申请日期 |
2012.02.09 |
申请人 |
PITTENGER MARK F.;GORDON STEPHEN L.;MACKAY ALASTAIR MORGAN |
发明人 |
PITTENGER MARK F.;GORDON STEPHEN L.;MACKAY ALASTAIR MORGAN |
分类号 |
A61K35/12;A61K48/00;A61P9/04;A61P9/10;C12N5/077;C12N5/0775 |
主分类号 |
A61K35/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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