发明名称 |
METHODS OF TREATING AND DIAGNOSING ACUTE CHEST SYNDROME |
摘要 |
<p>In certain embodiments, the disclosure relates to methods of treating or preventing organ inflammation or failure such as pulmonary inflammation comprising administering a heme scavenger such as hemopexin to a subject in need thereof. The subject may be diagnosed with higher than normal levels of protein-free plasma heme or a hemolytic disorder such as sickle cell disease, autoimmune hemolytic anemia, or paroxysmal nocturnal hemoglobinuria or acute lung injury or acute chest syndrome. Typically, the hemopexin is recombinant human hemopexin.</p> |
申请公布号 |
WO2012019178(A9) |
申请公布日期 |
2012.06.07 |
申请号 |
WO2011US46872 |
申请日期 |
2011.08.05 |
申请人 |
EMORY UNIVERSITY;OFORI-ACQUAH, SOLOMON;GHOSH, SAMIT |
发明人 |
OFORI-ACQUAH, SOLOMON;GHOSH, SAMIT |
分类号 |
A61K38/16;A61K38/46;A61K38/48;A61P11/00;A61P29/00 |
主分类号 |
A61K38/16 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|