| 发明名称 |
METHOD FOR TREATING CANCER USING IL-21 AND MONOCLONAL ANTIBODY THERAPY |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a method for enhancing the antitumor activity of monoclonal antibody therapy for patients that do not respond to monoclonal antibody therapy alone or in combination with other treatment therapy. <P>SOLUTION: There is provided a method for treating cancer by co-administering a therapeutically effective amount of a therapeutic monoclonal antibody which is rituximab or trastuzumab and a therapeutically effective amount of IL-21 polypeptide. <P>COPYRIGHT: (C)2012,JPO&INPIT |
| 申请公布号 |
JP2012102122(A) |
申请公布日期 |
2012.05.31 |
| 申请号 |
JP20110284589 |
申请日期 |
2011.12.27 |
| 申请人 |
ZYMOGENETICS INC |
发明人 |
KINDSVOGEL WAYNE R;HUGHES STEVEN D;HOLLY RICHARD D;CLEGG CHRISTOPHER H;FOSTER DONALD C;JOHNSON REBECCA A;HEIPEL MARK D;SIVAKUMAR PALLAVUR V |
| 分类号 |
A61K39/395;A61K38/00;A61K38/20;A61P35/00;A61P43/00;C07K14/54;C07K16/28;C07K16/32;C12N15/02;C12P21/08 |
主分类号 |
A61K39/395 |
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