| 发明名称 |
METHOD FOR TREATING CHRONIC LYMPHOCYTIC LEUKEMIA |
| 摘要 |
The present invention provides a method for treating a subject having chronic lymphocytic leukemia (CLL) comprising administering to the subject one or more agents that target cell surface membrane antigens expressed preferentially on cells of the proliferative compartment of a CLL clone of the subject to treat chronic lymphocytic leukemia in the subject. The present invention also provides a method for treating a subject having chronic lymphocytic leukemia comprising administering to the subject one or more agents that target cell surface membrane antigens expressed preferentially on cells of the “resting re-entry compartment” to treat chronic lymphocytic leukemia in the subject. |
| 申请公布号 |
US2012128586(A1) |
申请公布日期 |
2012.05.24 |
| 申请号 |
US201013377514 |
申请日期 |
2010.06.24 |
| 申请人 |
CALISSANO CARLO;CHIORAZZI NICHOLAS;DAMLE RAJENDRA N.;PATTEN PIERS;THE FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH |
发明人 |
CALISSANO CARLO;CHIORAZZI NICHOLAS;DAMLE RAJENDRA N.;PATTEN PIERS |
| 分类号 |
A61K39/395;A61K35/12;A61K38/02;A61K48/00;A61K49/00;A61K51/04;A61P35/02;C07H21/04;C07K2/00;C07K16/30;C12N5/0783;C12Q1/02 |
主分类号 |
A61K39/395 |
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