发明名称 TRITERPENOID DERIVATIVES USEFUL AS ANTIPROLIFERATIVE AGENTS
摘要 Formula (I) and (II). The present invention relates to the use of a new lupane derivative of general formula (I) or (II), or a pharmaceutically acceptable salt, crystal form, complex, hydrate, or hydrolysable ester thereof, for preventing and/or inhibiting tumor growth and for treating cancer and other proliferative diseases, more particularly for treating leukemia, liver, cervical, colon and prostate cancer. The present invention also relates to the synthesis of these compounds and to pharmaceutical compositions which contain them.
申请公布号 US2012129901(A1) 申请公布日期 2012.05.24
申请号 US201013321269 申请日期 2010.05.20
申请人 RIBEIRO SALVADOR JORGE ANTONIO;MENDES DOS SANTOS RITA CATARINA;CASCANTE SERRATOSA MARTA 发明人 RIBEIRO SALVADOR JORGE ANTONIO;MENDES DOS SANTOS RITA CATARINA;CASCANTE SERRATOSA MARTA
分类号 A61K31/4196;A61K31/4164;A61K31/4178;A61P35/00;A61P35/02;C07D233/60;C07D249/08;C07D403/12;C12Q1/18 主分类号 A61K31/4196
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