发明名称 HETEROCYCLIC COMPOUNDS AND EXPANSION AGENTS FOR HEMATOPOIETIC STEM CELLS
摘要 An expansion agent for hematopoietic stem cells and/or hematopoietic progenitor cells useful for improvement in the efficiency of gene transfer into hematopoietic stem cells for gene therapy useful for treatment of various disorders is provided. An expansion agent for hematopoietic stem cells and/or hematopoietic progenitor cells containing a compound represented by the formula (I) (wherein X, Y, Z, Ar1, R1, R2, R3, R4, R5, R6 and R7 are as defined in the description), a tautomer, prodrug or pharmaceutically acceptable salt of the compound or a solvate thereof, which can expand hematopoietic stem cells and/or hematopoietic progenitor cells.
申请公布号 US2012128640(A1) 申请公布日期 2012.05.24
申请号 US201013376280 申请日期 2010.06.04
申请人 NISHINO TAITO;IWAMOTO SHUNSUKE;MIYAJI KATSUAKI;NISSAN CHEMICAL INDUSTRIES LTD. 发明人 NISHINO TAITO;IWAMOTO SHUNSUKE;MIYAJI KATSUAKI
分类号 A61K35/28;A61K35/00;A61P7/00;A61P9/10;A61P19/00;A61P25/00;A61P37/04;A61P37/06;C07D333/32;C07D409/12;C07D409/14;C07D413/14;C12N5/02;C12N5/077;C12N15/85 主分类号 A61K35/28
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