发明名称 2,3-DIHYDRO-1H-INDENE-2-YLUREA DERIVATIVE AND PHARMACEUTICAL APPLICATION OF SAME
摘要 In order to provide a low molecular weight compound that has p38MAPK inhibitory activity and the accompanying TNF± production suppression activity and that has a favorable pharmacokinetic profile as a pharmaceutical and decreased hepatotoxicity, and to provide a pharmaceutical application of same, disclosed is a 2,3-dihydro-1H-indene-2-yl urea derivative represented below, a pharmacologically acceptable salt thereof, and a therapeutic agent or preventative agent that contains same as an active ingredient and that is for allergic dermatitis, inflammatory bowel disease, and pain.
申请公布号 KR20120050504(A) 申请公布日期 2012.05.18
申请号 KR20127008178 申请日期 2010.09.30
申请人 TORAY INDUSTRIES, INC. 发明人 KANEKO HIROAKI;KAWAI HIDEKI;IURA YOSUKE;INOUE HIDEKI;KAINO MIE;MEGURO HIROYUKI;UCHIDA TAZURU
分类号 C07C275/34;A61K31/17;A61P17/00;C07D295/12 主分类号 C07C275/34
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