| 发明名称 |
NOVEL N-SUBSTITUTED-PYRROLIDINES AS INHIBITORS OF MDM2-P-53 INTERACTIONS. |
| 摘要 |
<p>There are provided compounds of the formula (I) wherein X, Y, R<sub>1</sub>, R<sub>2</sub>, R<sub>3</sub>, R<sub>3</sub>, R<sub>4</sub>, and R<sub>5</sub> are as described herein and enantiomers and pharmaceutically acceptable salts and esters thereof which are useful as anticancer agents.</p> |
| 申请公布号 |
MX2012003982(A) |
申请公布日期 |
2012.05.08 |
| 申请号 |
MX20120003982 |
申请日期 |
2010.10.11 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG.* |
发明人 |
BARTKOVITS, DAVID JOSEPH;CHU, XIN-JIE;LIU, JIN-JUN;ROSS, TINA MORGAN;ZHANG, ZHUMING |
| 分类号 |
C07D207/16;A61K31/402;A61K31/4025;A61P35/00;C07D401/06;C07D401/12;C07D403/12 |
主分类号 |
C07D207/16 |
| 代理机构 |
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代理人 |
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