CANCER-METASTASIS SUPPRESSION BY MEANS OF INCREASED TASK-3 POTASSIUM CHANNEL EXPRESSION

摘要

The present invention relates to cancer-metastasis suppression by means of increased TASK-3 potassium channel expression. It has been confirmed that cancer-cell movement and invasion can be effectively controlled by regulating the level of TASK-3 expression; and provided is a new medical use for TASK-3 as a target molecule for cancer-metastasis suppression. Provided are: a pharmaceutical composition for suppressing cancer metastasis containing, as an active ingredient, a TASK-3 protein, a gene coding for a TASK-3 protein or a recombinant expression vector comprising the gene; a cancer-metastasis suppressing method using the same; a cancer-metastasis probability predicting kit; a method for selecting a cancer-metastasis risk group by using the kit; and a screening method for cancer-metastasis suppressing agents.