PIPERAZINYL AND PIPERIDINYL UREAS AS MODULATORS OF FATTY ACID AMIDE HYDROLASE

摘要

Disclosed are piperazinyl and piperidinyl urea compounds of formula (I) and their pharmaceutically acceptable salts, wherein the substituents are as described within the specification. An examples of a compound of formula (I) is 4-(3,4-dibromo-benzyl)-piperazine-1-carboxylic acid pyridine-4-ylamide. Further disclosed is a pharmaceutical composition comprising an effective amount of a compound of formula (I) and a pharmaceutically acceptable excipient, and the use of a compound of formula (I) in the preparation of a medicament for treating a disease, disorder, or medical condition mediated by FAAH activity.