| 发明名称 |
METHODS FOR TREATING PRURITUS BY ADMINISTERING AN ANTIBODY THAT SPECIFICALLY BINDS HUMAN PAR2 |
| 摘要 |
The present invention provides methods for treating pruritus by blocking human protease activated receptor-2 (PAR2) activity. The methods of the invention can be used to treat pruritus associated with atopic dermatitis, psoriasis, burn scarring, hypertrophic scarring, keloids, renal failure or hepatic failure. The methods of the invention include administering an antibody or antigen-binding fragment thereof that specifically binds human PAR2.
|
| 申请公布号 |
US2012093824(A1) |
申请公布日期 |
2012.04.19 |
| 申请号 |
US201113325098 |
申请日期 |
2011.12.14 |
| 申请人 |
MACDONALD LYNN;MURPHY ANDREW J.;PAPADOPOULOS NICHOLAS J.;MORRA MARC R.;SALZLER ROBERT R.;LACROIX-FRALISH MICHAEL L.;REGENERON PHARMACEUTICALS, INC. |
发明人 |
MACDONALD LYNN;MURPHY ANDREW J.;PAPADOPOULOS NICHOLAS J.;MORRA MARC R.;SALZLER ROBERT R.;LACROIX-FRALISH MICHAEL L. |
| 分类号 |
A61K39/395;A61P17/04 |
主分类号 |
A61K39/395 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
