摘要 |
<p>1,260,848. Hypotensive &c compositions. BOEHRINGER INGELHEIM G.m.b.H. 18 Dec., 1968 [18 Dec., 1967; 22 Dec., 1967; 29 April, 1968], No. 60149/68. Heading A5B. [Also in Division C2] Pharmaceutical compositions comprise a compound of the general formula: (R 1 =(CH 2 ) 0-3 -CN, (CH 2 ) 0-3 -NH 2 , (CH 2 ) 1-4 - OH, COOH, .C 2-5 alkoxycarbonyl, alkenoxy or alkynoxy; R 2 =H, halogen, alkyl, alkoxy or alkenyl containing up to 5 carbon atoms, CN, NO 2 ; or R 1+2 =3, 4-OCH 2 O-; R 3 =C 1-5 alkyl, except that R 3 contains at least 2 carbon atoms when R 1 =CN or NH 2 and R 2 simultaneously=halogen or alkyl; R 4 =C 2-6 alkyl) or salt thereof, with or without further active ingredients (e.g. coronary dilators and sympathicomimetics), in association with a carrier. The primary active ingredients possess #- adrenolytic and hypotensive activity.</p> |