发明名称 ANTIBODIES AGAINST HUMAN TWEAK AND USES THEREOF
摘要 <p>An antibody binding to TWEAK, characterized by binding to TWEAK characterized by comprising as heavy chain variable domain a CDR3H selected from the group consisting of SEQ ID NO: 8, 16 or 24 is useful for the treatment of cancer or autoimmune diseases, rheumatoid arthritis, psoratic arthritis, muscle diseases, e.g. muscular dystrophy, multiple sclerosis, chronic kidney diseases, bone diseases, e.g. bone degeneration in multiple myeloma, systemic lupus erythematosus, lupus nephritis, and vascular injury.</p>
申请公布号 CA2809632(A1) 申请公布日期 2012.04.12
申请号 CA20112809632 申请日期 2011.09.30
申请人 F. HOFFMAN-LA ROCHE AG 发明人 BAEHNER, MONIKA;KNOETGEN, HENDRIK;NIEWOEHNER, JENS
分类号 C07K16/24 主分类号 C07K16/24
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