发明名称 |
AZOLE DERIVATIVES AS WTN PATHWAY INHIBITORS |
摘要 |
The present invention relates to new compounds of formula I, to processes for their preparation, to pharmaceutical formulations containing such compounds and to their use in therapy. Such compounds find particular use in the treatment and/or prevention of conditions or diseases which are affected by over-activation of signaling in the Wnt pathway. For example, these may be used in preventing and/or retarding proliferation of tumor cells, for example carcinomas such as colon carcinomas. |
申请公布号 |
EP2438052(A1) |
申请公布日期 |
2012.04.11 |
申请号 |
EP20100727792 |
申请日期 |
2010.06.07 |
申请人 |
OSLO UNIVERSITY HOSPITAL HF |
发明人 |
HOLSWORTH, DAN;WAALER, JO;MACHON, ONDREJ;KRAUSS, STEFAN |
分类号 |
C07D401/04;A61K31/4196;A61P35/00;C07D413/12;C07D413/14 |
主分类号 |
C07D401/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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