发明名称 Combinations for the treatment of diseases involving cell proliferation
摘要 Disclosed are pharmaceutical compositions for the treatment of diseases which involve cell proliferation. Also disclosed are methods for the treatment of said diseases, comprising co-administration of a compound 1 of Formula (I) wherein the groups L, R1, R2, R3, R4 and R5 have the meanings given herein and of an effective amount of an active compound 2 and/or co-treatment with radiation therapy, in a ratio which provides an additive and synergistic effect, and to the combined use of a compound 1 of Formula (I) and of an effective amount of an active compound 2 and/or radiotherapy for the manufacture of corresponding pharmaceutical combination preparations.
申请公布号 US8143247(B2) 申请公布日期 2012.03.27
申请号 US20090437280 申请日期 2009.05.07
申请人 MUNZERT GERD;STEEGMAIER MARTIN;BAUM ANKE;BOEHRINGER INGELHEIM INTERNATIONAL GMBH 发明人 MUNZERT GERD;STEEGMAIER MARTIN;BAUM ANKE
分类号 A61K31/54;A01N43/58;A61K31/535;C07D417/00 主分类号 A61K31/54
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