Compositions and methods useful for treating influenza that include an influenza virus hemagglutinin antigen in combination with lipid vesicles that include a non-ionic surfactant (NISVs) and/or in combination with a TLR-3 agonist adjuvant are descibed. The compositions remain potent even when they are not stored in a standard cold-chain system (i.e., they are thermostable).
申请公布号
WO2012006368(A3)
申请公布日期
2012.03.15
申请号
WO2011US43095
申请日期
2011.07.06
申请人
VARIATION BIOTECHNOLOGIES, INC.;ANDERSON, DAVID, E.;OGREL, ANDREI;BOCH, RONALD, ERWIN;BAXTER, JEFF
发明人
ANDERSON, DAVID, E.;OGREL, ANDREI;BOCH, RONALD, ERWIN;BAXTER, JEFF