发明名称 |
NOVEL SPHINGOSINE KINASE TYPE 1 INHIBITORS, COMPOSITIONS AND PROCESSES FOR USING SAME |
摘要 |
<p>Provided are novel compositions which uniquely inhibit sphingosine kinase Type 1 (SphK1) and which are useful in a number of applications including killing or damaging cancer cells, inducing apoptosis, inhibiting growth, metastasis and development of chemoresistance in cancer cells, leukemia, increasing the effectiveness of anti-cancer agents, attenuating immune reactivity, inhibiting survival signaling in cancer cells, and reducing symptoms of multiple sclerosis.</p> |
申请公布号 |
EP2424554(A1) |
申请公布日期 |
2012.03.07 |
申请号 |
EP20100770316 |
申请日期 |
2010.04.29 |
申请人 |
ENZO THERAPEUTICS, INC.;VIRGINIA COMMONWEALTH UNIVERSITY |
发明人 |
ZIPKIN, ROBERT, ELLIOT;ADAMS, JEFFREY, KROLL;SPIEGEL, SARAH |
分类号 |
A61K36/254;A61K36/258;A61P35/00 |
主分类号 |
A61K36/254 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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