发明名称 |
A TUBERCULOSIS TB VACCINE TO PREVENT REACTIVATION |
摘要 |
<p>The present invention discloses a vaccine or immunogenic composition that can be administered to latently infected individuals to prevent reactivation of latent tuberculosis infection caused by species of the tuberculosis complex microorganisms (Mycobacterium tuberculosis., M. bovis, M. africanum), The invention is based on a number of M. tuberculosis derived proteins and protein fragments which are constitutively expressed in different stages of the infection. The invention is directed to the use of these polypeptides, immunologically active fragments thereof and the genes encoding them for immunological compositions such as vaccines.</p> |
申请公布号 |
EP2421557(A1) |
申请公布日期 |
2012.02.29 |
申请号 |
EP20100766664 |
申请日期 |
2010.04.23 |
申请人 |
STATENS SERUM INSTITUT |
发明人 |
DIETRICH, JES;ANDERSEN, PETER;LUNDBERG, CARINA, VINGSBO;HOANG, TRUC, THI, KIM, THAN |
分类号 |
A61K39/04;A61P11/00;C07K14/35;C07K19/00 |
主分类号 |
A61K39/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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