| 发明名称 |
Treating neurological disorders using selective antagonists of persistent sodium current |
| 摘要 |
The present invention provides methods of treating neurological disorders in a mammal by administering to the mammal an effective amount of a selective persistent sodium channel antagonist that has at least 20-fold selectivity for persistent sodium current relative to transient sodium current. |
| 申请公布号 |
US8124612(B2) |
申请公布日期 |
2012.02.28 |
| 申请号 |
US20060326263 |
申请日期 |
2006.01.05 |
| 申请人 |
EHRING GEORGE R.;ADORANTE JOSEPH S.;WHEELER LARRY A.;MALONE THOMAS;WHITCUP SCOTT M.;ALLERGAN, INC. |
发明人 |
EHRING GEORGE R.;ADORANTE JOSEPH S.;WHEELER LARRY A.;MALONE THOMAS;WHITCUP SCOTT M. |
| 分类号 |
A01N43/40;A01N43/82;A61K31/00;A61K31/136;A61K31/235;A61K31/381;A61K31/41;A61K31/435;A61K31/44;A61K31/4439 |
主分类号 |
A01N43/40 |
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