| 发明名称 |
SYTHESIS OF BIOLOGICALLY ACTIVE 4-ACYLAMINO-4,5,6,7-TETRAHYDROINDAZOLES |
| 摘要 |
The invention provides a novel method of synthesis of 4-acylamino-4,5,6,7-tetrahydroindazoles with general formula (I). The method consists of Ritter reaction between 4-hydroxy-4,5,6,7-tetrahydroindazoles or 6,7-dihydroindazoles and various nitriles in acidic medium which generates the corresponding tetrahydroindazolyl cation. Compounds (I) possess analgesic activity. |
| 申请公布号 |
LV14476(A) |
申请公布日期 |
2012.02.20 |
| 申请号 |
LV20110000167 |
申请日期 |
2011.12.07 |
| 申请人 |
R&Imacr,GAS TEHNISK&Amacr, UNIVERSIT&Amacr,TE |
发明人 |
TURKS M&Amacr,RIS;STRAKOVA INTA;GOROVOJS KIRILS;PIVEN YURY A.;KHLEBNIKAVA TATSIANA S.;LAKHVICH FIODOR A.;GOLUBEVA MARINA B.;KANTROUSKAYA INHA A. |
| 分类号 |
A61K31/416;C07D231/56 |
主分类号 |
A61K31/416 |
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