| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a method for producing crocetin pharmaceutical preparation suppressing precipitation produced when coloring beverage. <P>SOLUTION: This method for producing the crocetin pharmaceutical preparation includes preparing a dispersion liquid by dispersing crocetin shown by formula in a saccharide-containing aqueous solution, and at that time, adjusting the particle diameter of the dispersion liquid to below 0.5 μm in a median diameter. The adjustment is performed preferably by 1 path (single frequency treatment) or many passes (a plurality of frequency treatments) in about 5-80 MPa, using a high-pressure homogenizer (for instance, microfluidizer). <P>COPYRIGHT: (C)2012,JPO&INPIT |
