| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a safe and high capacity binder which selectively remove ions from the body with a lower drug dosage and a better patient compliance profile. <P>SOLUTION: There is provided a pharmaceutical composition comprising core-shell particles. In the pharmaceutical composition, the core-shell particles comprise a core component and a shell component and the core-shell particles in the animal subject are connected to the larger amount of inorganic ions in the presence of the shell component compared with the amount of those in the absence of the shell component and the inorganic ions are negative ions. <P>COPYRIGHT: (C)2012,JPO&INPIT |
