发明名称 |
NIOSOME HAVING METAL PORPHYRIN COMPLEX EMBEDDED THEREIN, PROCESS FOR PRODUCING THE SAME AND DRUG WITH THE USE THEREOF |
摘要 |
A niosome having a metalloporphyrin complex embedded therein comprising a cationized metalloporphyrin complex and a niosome-forming substance. The niosome having a metalloporphyrin complex embedded therein has an SOD activity, can interact with superoxide anionic radicals (O2−.) as a target, and can reduce these radicals without fail. The niosome having a metalloporphyrin complex embedded therein can reach cells in living bodies such as cancer cells due to properties of a niosome. Therefore, the niosome having a metalloporphyrin complex embedded therein can exhibit an excellent effect of treating cancer by reducing O2−. in cancer cells. In addition, since the effect is selective, the niosome can be used as a novel anticancer agent without side effects. Moreover, the niosome having a metalloporphyrin complex embedded therein can be retained in the blood while exhibiting a superior antioxidation effect. The niosome can thus protect living bodies from hindrance brought about by active oxygen species. |
申请公布号 |
US2012039987(A1) |
申请公布日期 |
2012.02.16 |
申请号 |
US201113183273 |
申请日期 |
2011.07.14 |
申请人 |
YUASA MAKOTO;OYAIZU KENICHI;YAMAGUCHI ARITOMO;HANYUU YUKIHIRO;KASAHARA KAZUNORI;KOMURO MASAYASU;MAKOTO YUASA |
发明人 |
YUASA MAKOTO;OYAIZU KENICHI;YAMAGUCHI ARITOMO;HANYUU YUKIHIRO;KASAHARA KAZUNORI;KOMURO MASAYASU |
分类号 |
A61K9/127;A61K31/409;A61K31/555;A61K45/06;A61P3/10;A61P9/10;A61P25/00;A61P29/00;A61P35/00;A61P39/06;A61P43/00 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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