| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide methods and compositions for modulating hepatocyte growth factor activator function. <P>SOLUTION: There is provided an isolated antibody that specifically binds human hepatocyte growth factor activator (HGFA). The invention relates to methods, compositions, kits and articles of manufacture for modulating hepatocyte growth factor activator (HGFA) function, thereby modulating physiological effects of HGFA activity. Modulation of HGFA function can be effected by the use of antibodies. The invention also relates to antagonists that disrupt the HGF/c-met signaling pathway. An antibody comprising a CDR-H1 region is also provided. <P>COPYRIGHT: (C)2012,JPO&INPIT |
