发明名称 |
Methods and Compositions for Managing Cancer Cell Growth |
摘要 |
The invention relates to composition and a method of using the composition for modulating proliferation, invasiveness, the expression of a biomarker of an abnormal cell, of reducing the risk of a patient cell becoming abnormal, or of modulating proliferation of a carcinoma-associated fibroblast or of a tumor-associated macrophage. The invention also relates to a method of culturing the composition to produce molecules that modulate abnormal cell proliferation, invasiveness, or metastasis. The composition comprises a biocompatible matrix and cells engrafted thereon.
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申请公布号 |
US2012027858(A1) |
申请公布日期 |
2012.02.02 |
申请号 |
US201013147695 |
申请日期 |
2010.02.04 |
申请人 |
FRANSES JOSEPH W.;EDELMAN ELAZER R.;CARDOSO ANGELO MANUEL DE ALMEIDA;NUGENT HELEN MARIE;MASSACHUSETTS INSTITUTE OF TECHNOLOGY |
发明人 |
FRANSES JOSEPH W.;EDELMAN ELAZER R.;CARDOSO ANGELO MANUEL DE ALMEIDA;NUGENT HELEN MARIE |
分类号 |
A61K35/12;A61K9/00;A61K38/18;A61P35/00;A61P35/04;C07K14/50;C12N5/071;C12N5/09;C12P21/00 |
主分类号 |
A61K35/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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