Use of DR3 antibodies in the treatment of inflammatory disease,申请号US20100771910-传众专利搜索

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发明名称	Use of DR3 antibodies in the treatment of inflammatory disease
摘要	The present invention relates to novel Death Domain Containing Receptor (DR3 and DR3-V1) proteins that are members of the tumor necrosis factor (TNF) receptor family. In particular, isolated nucleic acid molecules are provided encoding the human DR3 and DR3-V1 proteins. DR3 and DR3-V1 polypeptides are also provided, as are vectors, host cells and recombinant methods for producing the same. Also provided are antibodies and fragments thereof that bind to polypeptides of the invention. The invention further relates to screening methods for identifying agonists and antagonists of DR3 and DR3-V1 activity.
申请公布号	US8105589(B2)	申请公布日期	2012.01.31
申请号	US20100771910	申请日期	2010.04.30
申请人	YU GUO-LIANG;NI JIAN;GENTZ REINER L.;DILLON PATRICK J.;HUMAN GENOME SCIENCES, INC.	发明人	YU GUO-LIANG;NI JIAN;GENTZ REINER L.;DILLON PATRICK J.
分类号	A61K39/395;A61K38/00;A61K48/00;C07K14/47;C07K14/705;C07K16/18;C07K16/28	主分类号	A61K39/395
代理机构		代理人
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