发明名称 Pharmaceutically stable compound consisting of timolol, dorzolamide and brimonidine
摘要 The present invention is related to ophthalmic formulations for the treatment of ocular ailments. More specifically, it is related to the pharmaceutical industry in the production of ophthalmic medication for the treatment of ocular hypertension. The advantage of the present invention over other state of the art treatments is that it achieves a composition of Dorzolamide Hydrochloride, Timolol Maleate and Brimonidine Tartrate with excellent properties of stability; it does not give rise to chemical reactions which produce modifications in the active molecules; with no antagonistic effects among the components. The present invention consists of a stable pharmaceutical composition for the treatment of ocular hypertension characterized by consisting of the following excipients: Polyoxyl 40 Stearate, Sodium Borate crystals, Sodium Chloride, Mannitol and Benzalkonium chloride.
申请公布号 PL2036538(T3) 申请公布日期 2012.01.31
申请号 PL20040083800T 申请日期 2008.01.10
申请人 发明人 TORNERO MONTANO JOSE RUBEN;BAIZA DURAN LEOPOLDO MARTIN;QUINTANA HAU JUAN DE DIOS
分类号 A61K9/00;A61K31/382;A61K31/498;A61K31/535 主分类号 A61K9/00
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