N-α-(BENZYLOXYCARBONYL)-L-γ-GLUTAMYL-3-[[2-[[BIS[BIS(2-CHLOROETHYL)AMINO]PHOSPHINYL]OXY]ETHYL]-SULFONYL]-L-ALANYL-2(R)-PHENYLGLICINE OR SALT THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING THAT COMPOUND, USE THEREOF FOR TREATMENT OF CANCER AND METHOD FOR TREATMENT OF CANCER USING SAID COMPOUND
摘要
The invention describes a compound N-α-(Benzyloxycarbonyl)-L-γ-glutamyl-3-[[2-[[bis[bis(2-chloroethyl)amino]phosphinyl]oxy]ethyl]-sulfonyl]-L-alanyl-2(R)-phenylglycine or a salt thereof, pharmaceutical composition containing that compound for the treatment of cancer and also a method for the treatment of cancer in a mammal, comprising administration of the compound to a mammal.
申请公布号
EA016052(B1)
申请公布日期
2012.01.30
申请号
EA20070001180
申请日期
2005.11.23
申请人
TELIK, INC.
发明人
BOULANGER WILLIAM, A.;COLLIER STEVEN, J.;EASTHAM STEPHEN, A.;EDIE DENIS, L.;GUEVEL RONAN, Y.;HERNANDEZ ABAD PEDRO, E.;HERR JASON, R.;KJAERSGAARD HANS, J.;MECKLER HAROLD;POLOMSKI ROBERT, E.;SCHOW STEVEN, R.;ZHICHKIN PAVEL, E.