发明名称 DERIVATIVES OF PYRROLIZINE, INDOLIZINE AND QUINOLIZINE, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF
摘要 Compound corresponding to the general formula in which m and n are each the number 1 or 2, Ar is a group chosen from phenyl, naphth-1-yl, naphth-2-yl, pyridin-2-yl, pyridin-3-yl, pyridin-4-yl, furan-2-yl, furan-3-yl, thien-2-yl, thien-3-yl, thiazol-2-yl and oxazol-2-yl groups, it being possible for this group Ar to be optionally substituted; R is either a hydrogen atom, or one or more substituents, which may be identical to or different from one another, chosen from halogen atoms and mono- or polyfluoro(C-C)alkyl and mono- or polyfluoro (C-C)alkyloxy, linear (C-C)alkyl, branched or cyclic (C-C)alkyl, (C-C)cycloalkyl(C-C)alkyl, (C-C)alkoxy, (C-C)cycloalkyloxy, (C-C)cycloalkyl(C-C)alkyloxy, (C-C)alkylthio, cyano, amino, phenyl, acetyl, benzoyl, (C-C)alkylsulphonyl, carboxyl, (C-C)alkoxycarbonyl and pentafluorosulphanyl groups. Therapeutic use.
申请公布号 EA015974(B1) 申请公布日期 2012.01.30
申请号 EA20090070312 申请日期 2007.09.21
申请人 SANOFI-AVENTIS 发明人 DARGAZANLI GIHAD;ESTENNE-BOUHTOU GENEVIEVE;MEDAISKO FLORENCE;RENONES MARIA, CARMEN
分类号 A61K31/437;C07D471/04;C07D487/04 主分类号 A61K31/437
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