发明名称 |
COMBINATION THERAPY FOR TREATING DIABETES AND CONDITION RELATED TO DIABETES, AND TREATING CONDITION TO BE IMPROVED WITH INCREASE IN BLOOD GLP-1 LEVEL |
摘要 |
<P>PROBLEM TO BE SOLVED: To provide a composition and a method for treating or preventing diabetes and a condition related to diabetes, and for increasing blood GLP-1 level in mammals. <P>SOLUTION: There is provided a combination of a specific amount of GPR 119 agonist and a specific amount of DPP-IV inhibitor. The combination has a better effect on a decrease in a blood glucose level or an increase in blood GLP-1 level in a subject than in the case of using only a specific amount of GPR 119 agonist or only a specific amount of DPP-IV inhibitor. The combination is therefore provided for treating or preventing diabetes and a condition related to diabetes, and for a condition to be improved with an increase in blood GLP-1 level. <P>COPYRIGHT: (C)2012,JPO&INPIT |
申请公布号 |
JP2012017330(A) |
申请公布日期 |
2012.01.26 |
申请号 |
JP20110172381 |
申请日期 |
2011.08.05 |
申请人 |
ARENA PHARMACEUTICALS INC |
发明人 |
CHU ZHI-LIANG;LEONARD JAMES N;AL-SHAMMA HUSSIEN A;JONES ROBERT M |
分类号 |
A61K45/06;A61P1/18;A61P3/04;A61P3/06;A61P3/10;A61P5/48;A61P9/10;A61P9/12;A61P13/12;A61P25/02;A61P25/08;A61P25/14;A61P25/16;A61P25/28;A61P27/02;A61P27/12;A61P43/00;C12Q1/02;G01N33/15;G01N33/50 |
主分类号 |
A61K45/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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