The present disclosure provides an isolated or recombinant IL-23-binding protein comprising an antigen binding domain of an antibody, wherein the antigen binding domain specifically binds to IL-23 but does not significantly bind to an IL-12p40 subunit and does not significantly bind to an IL-23p19 subunit when they are not components of IL-23. The present disclosure also provides uses of the IL-23-binding protein.
申请公布号
WO2012009760(A1)
申请公布日期
2012.01.26
申请号
WO2011AU00923
申请日期
2011.07.20
申请人
CEPHALON AUSTRALIA PTY LTD;CLARKE, ADAM, WILLIAM;DOYLE, ANTHONY, G;POLLARD, MATTHEW;TRAN, STEPHEN
发明人
CLARKE, ADAM, WILLIAM;DOYLE, ANTHONY, G;POLLARD, MATTHEW;TRAN, STEPHEN