METHOD TO IMPROVE GLYCOSYLATION PROFILE AND TO INDUCE MAXIMAL CYTOTOXICITY FOR ANTIBODY

摘要

The present invention relates to the production of recombinant glycoproteins or antibodies that have an improved glycosylation profile and effector functions such as ADCC and/or CDC. The present invention is in particular related to the production of glycoproteins or antibodies having a valuable glycosylation profile, especially a low fucose level and/or a high oligomannose level and /or presence of sialic acid to the glycans.