Aptamer for chymase, and use thereof

摘要

An aptamer which can bind to chymase to inhibit the activity of chymase and comprises the nucleotide sequence represented by the formula: XGAUAGANNUAAX (wherein X and X independently represent A or G; and N and N independently represent A, G, C, U or T); a complex comprising the aptamer and a functional substance (e.g., an affinity substance, a labeling substance, an enzyme, a drug delivery medium, or a medicinal agent); a medicinal agent or a reagent comprising the aptamer or the complex; a chymase detection method or a chymase purification method characterized by utilizing the aptamer or the complex; and others.