发明名称 |
Ovarian Cancer Methylome |
摘要 |
The present invention provides methods and kits for identifying a cell that exhibits or is predisposed to exhibiting unregulated growth by detecting hypermethylation of a gene or a regulatory region in at least one gene in the cell. Also provided are methods for diagnosis or prognosis of ovarian cancer in a subject. Also provided are methods of ameliorating ovarian cancer in a subject by administering to the subject an agent that demethylates a hypermethylated gene or regulatory region thereof. |
申请公布号 |
US2012014871(A1) |
申请公布日期 |
2012.01.19 |
申请号 |
US201013203480 |
申请日期 |
2010.02.26 |
申请人 |
HOQUE MOHAMMAD O.;BRAIT MARIANA;MALDONADO LEONEL |
发明人 |
HOQUE MOHAMMAD O.;BRAIT MARIANA;MALDONADO LEONEL |
分类号 |
A61K51/10;A61K31/706;A61K31/7068;A61P35/00;C12Q1/68 |
主分类号 |
A61K51/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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