COMPOSITION OF EXTENDED RELEASE TABLET CONTAINING TACROLIMUS

摘要

PURPOSE: A composition containing tacrolimus for sustained release oral administration is provided to release tacrolimus effect for 14 hours. CONSTITUTION: A composition for sustained release oral administration contains tacrolimus as an active ingredient, a mixture of hydroxypropyl beta-cyclodextrin and dioctylsulfosuccinate as an excipient, a mixture of hydroxypropylmethyl cellulose and ethyl cellulose as a sustained release excipient.